Two people are in local hospitals with serious injuries following a four-vehicle chain reaction crash on Highway OO alongside I-44 in Strafford.
It happened during the afternoon rush around 4:57 p.m. Tuesday.
Troopers say a driver speeding in a pickup rear-ended a car, causing two more cars to be hit head-on.
One driver was thrown from their vehicle, and crews had to cut through a car to get to another victim.
The Highway Patrol says two of the drivers, Jason Hahn, 44, Springfield and Glenda Cantrell, 59, Marshfield, were taken by ambulances to separate hospitals in Springfield.
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